Introducing, Nighty Night Fatty!

Sleep is essential to health, well-being and longevity.

Without adequate sleep, you can kiss your performance in the gym (and wistful aspirations for “gainzzz”) good-bye.

Is it possible to still have a PR-smashing working after a single night of poor sleep?

Of course. We’ve all done it.

But try continuing to shortchange your nightly repose, and just see how frequently you’re able to make quantifiable progress in the gym.

To make matters worse, your ability to build muscle and strength isn’t the only thing that’s limited by your sh***y sleep habits -- so, too, are your metabolism and weight loss/body recomposition goals.

To be blunt (and yes this will offend the snowflakes), but you need to get your f***ing sleep in order!

Apollon Nutrition already offers several options that help to reduce stress and improve sleep quality, including Chill Pills, Chill Until Tomorrow, and From Dusk Till Dawn.

However, we’ve cooked up something special for those of you looking to maximize body recomposition overnight.

Introducing, Nighty Night Fatty!

What is Nighty Night Fatty?

Nighty Night fatty is a stimulant-free body recomposition catalyst and sleep aid to help you fall asleep easier, sleep longer, and boost metabolism overnight so that you wake up feelings refreshed, energized, and in better shape.

What’s in Nighty Night Fatty?

At a high level, Nighty Night Fatty includes the most prominent, research-backed nighttime relaxation and sleep enhancers plus a few choice non-stimulant metabolic boosters and lipid annihilators to help you shave off  “that little bit extra” during your slumber.

L-Glycine

• Amino acid used as a building block for the body’s primary inhibitory (“calming”) neurotransmitter -- GABA
• Research in humans finds that 3g of glycine before bed may improve sleep quality and reduce feelings of sleepiness and fatigue during the day.[1,2]
• Pre-sleep glycine supplementation has also been found to significantly improve feelings of daytime fatigue, liveliness, “peppiness,” and “clear-headedness.”[3]

GABA

• GABA supplementation has been found to be an effective natural relaxant, comparable to that of L-Theanine (another ingredient found in Nighty Night Fatty).[4,5]

L-Carnitine L-Tartrate

• Carnitine is an essential nutrient required for energy production.
• It serves as the metabolic “taxi” that shuttles fatty acids into your cells so that it can efficiently burn fat for fuel.
• In addition to aiding fat metabolism, supplementation with L-Carnitine L-Tartrate has also been found to reduce muscle damage and promote greater recovery.[6]

Zylaria

• Novel proprietary extract of Xylaria nigripes, Cuscuta Chinensis, and Panax notoginseng developed by NuLiv Science
• Benefits GABA levels by aiding GABA function in the brain as well as the uptake of GABA to specific brain receptors[7]

Lemon Balm

• A relative of mint, lemon balm (Melissa officinalis) has been used for centuries as a natural means to reduce stress and anxiety as well as promote sleep
• Human studies have found that lemon balm supplementation can improve mood, reduce stress, and improve cognitive function[8,9,10,11]:

MitoBurn (L-BAIBA)

• Molecule naturally produced by the body during exercise that helps to regulate carbohydrate and fat metabolism[12]
• BAIBA may also help promote the “browning” of adipose tissue and defend against high-fat diet-induced obesity

L-Theanine

• “Calming” amino acid found predominantly in green tea leaves
• Can increase levels of serotonin and GABA, which can improve sleep while reducing feelings of stress or over-stimulation
• Furthermore, L-Theanine has been found to reduce psychological stress and sleep disturbances and improve sleep quality[13,14]

L-Ornithine

• Amino acid that plays a central role in the urea cycle and aids in the detoxification of the liver
• 400mg / day improves sleep quality markers in highly-stressed individuals[20,21]

InnoSlim

• Research-backed blend of highly purified Panax notoginseng root and astragalus membranaceus root extracts developed by NuLiv Science
• Bioactives naturally present in InnoSlim (e.g. ginsenosides) can inhibit glucose uptake up to 41% within the small intestine
• Additional studies note that InnoSlim may enhance glucose uptake into the muscle cells, supporting stable blood glucose levels and muscle energy generation
• Recent human studies showed that daily supplementation with InnoSlim significantly reduced blood glucose levels (10.1%), triglycerides (31.06%) and small dense low-density lipoprotein-cholesterol (19.96%) compared with the placebo

Sensoril

• Ashwagandha has been used for centuries in Ayurveda to improves the body’s ability to encounter, perceive, and recover from stress -- one of the major contributors to poor sleep
• Sensoril is a premium form of ashwagandha extract, containing both roots and leaves, that is standardized to 10% withanolides -- main phytoactive compounds in ashwagandha.
• Numerous studies have found that Sensoril can help decrease stress and anxiety while improving sleep quality[15]

AstraGin

• Clinically studied and patented blend of astragalus and panax notoginseng that improves nutrient bioavailability and promotes gut health

Melatonin

• Naturally produced by the body and dictates each individual’s circadian rhythm
• Exposure to blue light from electronics blunts melatonin synthesis making it harder to fall (and remain) asleep
• Melatonin supplementation has been shown to be effective for improving sleep quality and decreasing sleep latency.[16,17]
• May support weight loss by enhancing brown fat thermogenesis as well as help to reduce body weight, independent of calorie restriction[18,19]

Included ZMA Stack!

• A powerful combination of zinc, magnesium, and B6 used by athletes to help address common nutrient deficiencies in highly-stressed individuals that supports enhanced recovery, hormone levels, and sleep quality

Suggested Use

Due to the potency of Nighty Night Fatty, we suggest beginning with a ½ serving (½ scoop) and assessing tolerance.

If tolerated well, you may use up to a full serving (1 scoop) one time per day (30-60 minutes before bed).

Stacking Options

Nighty Night Fatty offers a complete solution for individuals looking to reduce stress, improve sleep, support recovery and encourage weight loss.

As such, we do not recommend stacking Nighty Night Fatty with other stress-relief or sleep aids.

It may be combined with other non-stimulant and non-sleep aids, including:

• 50/50 Formula-X
• ISOBlast
• Casein
• 50/50 Formula-V
• Egg-Cellent
• Chainsaw
• Enigma
• Collagen
• Kidney Kindness
• Liver Lover
• Resistance
• Gut Glory
• Alpha of Omegas

References

1. Bannai M, Kawai N, Ono K, Nakahara K, Murakami N. The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Front Neurol. 2012;3:61.
2. Bannai M, Kawai N. New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep. J Pharmacol Sci. 2012;118(2):145-8. doi: 10.1254/jphs.11r04fm. Epub 2012 Jan 27. PMID: 22293292.
3. INAGAWA, K., HIRAOKA, T., KOHDA, T., YAMADERA, W. and TAKAHASHI, M. (2006), Subjective effects of glycine ingestion before bedtime on sleep quality. Sleep and Biological Rhythms, 4: 75-77. https://doi.org/10.1111/j.1479-8425.2006.00193.x
4. Abdou, A. M., Higashiguchi, S., Horie, K., Kim, M., Hatta, H., & Yokogoshi, H. (2006). Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. BioFactors (Oxford, England), 26(3), 201–208.
5. Hepsomali, P., Groeger, J. A., Nishihira, J., & Scholey, A. (2020). Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review . In Frontiers in Neuroscience  (Vol. 14). https://www.frontiersin.org/articles/10.3389/fnins.2020.00923
6. https://www.sciencedirect.com/science/article/abs/pii/S0026049509004879
7. https://nulivscience.com/ingredients/zylaria/
8. Kennedy DO, Little W, Haskell CF, Scholey AB. Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress. Phytother Res. 2006;20:96–102. doi: 10.1002/ptr.1787.
9. Scholey A, Gibbs A, Neale C, et al. Anti-stress effects of lemon balm-containing foods. Nutrients. 2014;6(11):4805-4821. Published 2014 Oct 30. doi:10.3390/nu6114805
10. Kennedy DO, Scholey AB, Tildesley NT, Perry EK, Wesnes KA. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm) Pharmacol Biochem Behav. 2002;72:953–964. doi: 10.1016/S0091-3057(02)00777-3.
11. Kennedy DO, Wake G, Savelev S, Tildesley NT, Perry EK, Wesnes KA, Scholey AB. Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis(Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties. Neuropsychopharmacology. 2003;28:1871–1881. doi: 10.1038/sj.npp.1300230.
12. Tanianskii DA, Jarzebska N, Birkenfeld AL, O'Sullivan JF, Rodionov RN. Beta-Aminoisobutyric Acid as a Novel Regulator of Carbohydrate and Lipid Metabolism. Nutrients. 2019;11(3):524. Published 2019 Feb 28. doi:10.3390/nu11030524
13. Kim S, Jo K, Hong KB, Han SH, Suh HJ. GABA and l-theanine mixture decreases sleep latency and improves NREM sleep. Pharm Biol. 2019 Dec;57(1):65-73. doi: 10.1080/13880209.2018.1557698. PMID: 30707852; PMCID: PMC6366437.
14. Lyon MR, Kapoor MP, Juneja LR. The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. Altern Med Rev. 2011 Dec;16(4):348-54. PMID: 22214254.
15. Speers AB, Cabey KA, Soumyanath A, Wright KM. Effects of Withania somnifera (Ashwagandha) on Stress and the Stress- Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021;19(9):1468-1495. doi: 10.2174/1570159X19666210712151556. PMID: 34254920; PMCID: PMC8762185.
16. Iomski A. Melatonin Improves Sleep in Patients With Circadian Disruption. JAMA. 2018;320(8):749. doi:10.1001/jama.2018.10903
17. Sletten TL, Magee M et al. Efficacy of melatonin with behavioral sleep-wake scheduling for delayed sleep-wake phase disorder: A double blind, randomized clinical trial (2018). Efficacy of melatonin with behavioral sleep-wake scheduling for delayed sleep-wake phase disorder: A double blind, randomized clinical trial. PLOS Medicine 15(6): e1002587. https://doi.org/10.1371/journal.pmed.1002587
18. Tan DX, Manchester LC, et al. Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity.Obes Rev 2011; 12, 167-188.
19. Halpern, B., Mancini, M. C., Bueno, C., Barcelos, I. P., Edna de Melo, M., Lima, M. S., Cipolla-Neto, J. (2019). Melatonin Increases Brown Adipose Tissue Volume and Activity in Melatonin Deficient Patients: a Proof-of-Concept Study. Diabetes, db180956. https://doi.org/10.2337/db18-0956
20. Horiuchi M, Kanesada H, Miyata T, Watanabe K, Nishimura A, Kokubo T, Kirisako T. Ornithine ingestion improved sleep disturbances but was not associated with correction of blood tryptophan ratio in Japanese Antarctica expedition members during summer. Nutr Res. 2013 Jul;33(7):557-64. doi: 10.1016/j.nutres.2013.05.001. Epub 2013 Jun 12. PMID: 23827130.
21. Miyake M, Kirisako T, Kokubo T, Miura Y, Morishita K, Okamura H, Tsuda A. Randomised controlled trial of the effects of L-ornithine on stress markers and sleep quality in healthy workers. Nutr J. 2014 Jun 3;13:53. doi: 10.1186/1475-2891-13-53. PMID: 24889392; PMCID: PMC4055948.